The CDTI Innovation seeks a Spanish company to collaborate with Egypt in the development of a nanoplatform for the treatment of periodontitis

The initiative aims to develop a solution based on nanotechnology and photodynamic therapy to address some of the limitations of conventional treatments

Búsqueda de socios Egipto 4nov26
The proposal seeks to move towards new therapeutic solutions for adult and pediatric patients
INTERNATIONAL TECHNOLOGY COOPERATION

The University of Sinai (Egypt) is looking for a Spanish company to collaborate in an R&D project focused on the development of nanotreatments for periodontitis. The search is launched by Dr. Somia Ghabar, professor at this university, proposes to develop a nanoplatform to improve the treatment of this disease through photodynamic therapy.

The proposal starts from the limitations of conventional treatments, both mechanical and based on antibiotics, which can be conditioned by the depth of the periodontal pockets, antimicrobial resistance and the contraindications of some treatments in pediatric patients.

To address these challenges, the project proposes the synthesis, characterization and evaluation of a nanoplatform formed by liposomes and chitosan and loaded with Ce6 (Ce6-LCNPs), destined to the photodynamic therapy guided by nanotheranostic in models of periodontitis of adults and pediatric patients.

The technical and experimental scope of the project includes:

  • Formulation and engineering: Synthesis of liposomes by thin-film hydration (DPPC, cholesterol, DSPE-PEG2000), Ce6 loading and chitosan coating to promote stability, positive surface loading and mucoadhesion.
  • Dual nanotheranostic functionality: Use of Ce6 fluorescence to visualize the nanoplatform and monitor its distribution, along with irradiation by light of 660 nm to generate reactive oxygen species.
  • Antimicrobial and anti-biofilm tests: [Evaluation of bacterial eradication and biofilm destruction against P. gingivalis, A. actinomycetemcomitans, Fusobacterium nucleatum and Streptococcus mutans].
  • Biosecurity and comparative evaluation: Evaluation of cytocompatibility in human gingival fibroblasts (HGF-1) and periodontal ligament stem cells (hPDLSCs/dPDLSCs), along with comparative efficacy analyses in both adult and pediatric periodontitis models.

The proposed proposal aims to present the call for proposals for the 2026 Spain-Egypt R&D, called ESIP (Egypt Spain Innovation Programme), whose deadline for submission will remain open until December 3, 2026.

Interested entities can consult more information on the search for a partner and a summary of the proposal in this link.

 

Contact

For additional information on the technical scope of the proposal and the role of the Spanish company, you can contact Dr. Somia Ghabar via email somia.ghabar@su.edu.eg.

For information and advice on this search for partners and/or the ESIP call, you can contact the Office of the Delegation of North Africa and Middle East of the CDTI Innovation:

 

CDTI Innovation

The Center for Technological Development and Innovation, CDTI E.P.E. It is the innovation agency of the Ministry of Science, Innovation and Universities, whose objective is the promotion of technological innovation in the business environment. The mission of the CDTI is to ensure that the Spanish business fabric generates and transforms scientific and technical knowledge into globally competitive, sustainable and inclusive growth. 
 

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